Epithalon is the oldest research story in the catalog, a four amino acid peptide whose history runs back through decades of Russian gerontology research. This overview covers what epithalon is, where it comes from, what makes a tetrapeptide analytically distinctive, and how it is verified.
What Epithalon Is
Epithalon is a synthetic tetrapeptide: alanine, glutamate, aspartate, glycine. It was designed as the defined, synthetic successor to epithalamin, a pineal gland extract studied for decades in Soviet and Russian gerontology. The move from extract to synthetic peptide followed the standard logic of tool development: an extract is a mixture that varies by preparation, while a synthetic tetrapeptide is a single defined molecule that supports reproducible work in cellular aging models.
Another Branch of the Russian Tradition
Like semax and selank, epithalon carries a research record written largely in Russian, produced by the St. Petersburg school of peptide gerontology rather than the Moscow neuropeptide groups. The same caveat applies: the literature is deeper than an English search reveals and takes more effort to evaluate. Our article on Semax and Selank, the Russian neuropeptides covers the sibling tradition, and researchers evaluating epithalon inherit the same translation problem in a different subfield of the cognitive and longevity research category.
Verifying a Tetrapeptide
Four residues make epithalon one of the smallest molecules in the catalog, and the analytical logic mirrors what applies to KPV: identity confirms cleanly by mass spectrometry at this size, but purity methods must be matched to a small, highly polar molecule, and there is little sequence to distinguish the target from synthesis byproducts. A credible certificate shows identity, a purity value from an appropriate method, and net peptide content connecting the document to the vial. Our guide to reading a certificate of analysis for peptides explains each field, and certificates for our catalog are published through the COA portal.
Stability and Handling
A small peptide with no cysteine and no modifications, lyophilized epithalon is a stable material stored cold, dry, and protected from light, with the usual preference for refrigerated solutions and minimal freeze thaw cycling.
Research Use Only
Epithalon is supplied strictly for laboratory research by qualified professionals. It is not for human or veterinary use of any kind. Nothing in this overview is a protocol, a recommendation, or a claim of therapeutic effect.
Research compounds in this article
For research use only. Not for human consumption. Every product ships with a published certificate of analysis.