Sermorelin is the first 29 amino acids of growth-hormone-releasing hormone, GRF(1-29), the shortest fragment of the native hormone that retains full activity at the GHRH receptor. It is the founding molecule of the GHRH-analogue research family and carries one of the longest study histories of any peptide in this catalog. Heartland Bio Labs supplies sermorelin for laboratory research in 5mg and 10mg vials with independent purity and identity verification.
What sermorelin is
When researchers mapped GHRH in the 1980s, they found that its first 29 residues did the receptor's work and the remaining 15 were dispensable. Sermorelin is that discovery made into a molecule: the minimal fully functional GHRH fragment. Unmodified, it keeps the native sequence's short half-life, which for some research designs is exactly the property wanted, a clean, brief receptor stimulus rather than the extended exposure of stabilized analogues. The structural profile is in our sermorelin research overview.
Where sermorelin sits in the family
Sermorelin sits on the GHRH-receptor side of a larger family of growth hormone axis peptides. Our GH-axis peptide family map shows where it fits and how the GHRH-analogue side differs from the ghrelin-receptor side.
Every GHRH analogue in research use descends from the same 29-residue core. Tesamorelin keeps the full 44-residue hormone and stabilizes its N-terminus. CJC-1295 takes the 1-29 fragment and engineers it for a half-life of days. Sermorelin is the unmodified reference point the others are measured against, which is precisely its research value: programs comparing stabilization strategies need the baseline molecule. On the other side of the axis, ipamorelin works through the ghrelin receptor rather than the GHRH receptor, and the CJC-1295 + ipamorelin blend serves programs studying both pathways at once.
Product characteristics
- Synthetic 29-amino acid peptide: GRF(1-29), the minimal active GHRH fragment
- Approximate molecular weight: 3,358 g/mol
- Native, unmodified sequence; the reference molecule of the analogue family
- Supplied as white lyophilized powder in sealed vials
- Available strengths: 5mg and 10mg
- HPLC purity and mass spectrometry identity, tested by an independent laboratory
- For laboratory research use only
How this product is verified
Sermorelin is tested by an independent analytical laboratory, HPLC for purity and mass spectrometry for identity, with certificates published in our COA portal for review before ordering. The name sells heavily across this market, mostly through clinics, and material quality varies accordingly. The checklist in our guide to vetting a research peptide supplier separates documented material from labeled material in about five minutes.
Strengths and pricing
Sermorelin ships in 5mg vials at $49 and 10mg vials at $85, both in stock. The 10mg vial works out meaningfully cheaper per milligram for programs running repeated work. Orders before 2:00 PM Central dispatch same-day from the Tulsa, Oklahoma area, and institutional quantities run through our wholesale program.
Storage and handling
Keep lyophilized vials sealed, cool, dry, and away from light, refrigerated for the long term. Reconstitute with bacteriostatic water and refrigerate the solution, using it within the window your research protocol defines.
Reconstitution math
Work out concentration (mg/mL), amount per volume and molarity for any vial size with the general peptide calculator. For the bench procedure see how to reconstitute peptides.
Research use only
Sermorelin from Heartland Bio Labs is sold strictly for laboratory research and identification purposes. It is not a drug, it has not been evaluated by the FDA, and it is not for human or veterinary use of any kind. By purchasing, you affirm that you are qualified to handle research compounds and agree to our research use policy.
