IGF-1 LR3 (Long Arg-3 Insulin-like Growth Factor 1) is a recombinant 83-amino-acid analog of human IGF-1, modified with an N-terminal arginine-rich extension and an Arg-3 substitution that confers extended biological activity in cell culture systems. It has been studied extensively in preclinical research models of cell proliferation, growth factor signaling, and skeletal muscle biology. Heartland Bio Labs supplies IGF-1 LR3 as a high-purity lyophilized research compound for qualified laboratory and research use only.
IGF-1 LR3
- ≥99% HPLC
- Mass Spec Verified
- COA Per Lot
- US Lab
IGF-1 LR3 (Long Arg-3 Insulin-like Growth Factor 1) is a recombinant 83-amino-acid analog of human IGF-1, modified with an N-terminal arginine-rich extension and an Arg-3 substitution that confers extended biological activity in cell culture systems. It has been studied extensively in preclinical research models of cell proliferation, growth factor signaling, and skeletal muscle biology. Heartland Bio Labs supplies IGF-1 LR3 as a high-purity lyophilized research compound for qualified laboratory and research use only.
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IGF-1 LR3 is among the most widely used IGF-1 analogs in published cell biology and growth factor research. In vitro and in vivo studies have investigated its activity in myoblast cell lines, fibroblast cultures, and animal tissue models, with research interest focused on IGF-1 receptor binding kinetics, IGFBP interaction profiles, downstream PI3K/Akt signaling, and skeletal muscle satellite cell behavior. It is commonly used in academic literature as a long-acting reference analog of native IGF-1.
This compound is supplied strictly for research purposes. No clinical or therapeutic application is implied or represented.
Product Characteristics
- Peptide class: Recombinant IGF-1 analog (83 amino acids)
- Origin: Modified human IGF-1 sequence with N-terminal extension and Arg-3 substitution
- Form: Lyophilized powder
- Reconstitution medium: Bacteriostatic water, sterile water, or 0.6% acetic acid (research standard)
- Appearance: White to off-white powder
| Purity | ≥99% HPLC |
|---|
Handling Information
IGF-1 LR3 should be handled under standard laboratory conditions. Use appropriate personal protective equipment. Avoid repeated freeze-thaw cycles once reconstituted. Handle with care to minimize degradation of the peptide structure. This compound is intended for use by qualified research professionals only.
Storage Requirements
- Long-term (lyophilized): Store at -20°C, protected from light and moisture
- Short-term (reconstituted): Store at 4°C; use within 28 days
- Do not store near solvents, acids, or strong oxidizing agents
- Keep in original vial with cap sealed until point of use
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How should I store this peptide?+
Lyophilized peptides should be stored at −20°C in a dry, light-protected environment. Avoid repeated freeze-thaw cycles. Once reconstituted, store at 2-8°C and use within 4-8 weeks depending on the compound.
What should I reconstitute it with?+
Bacteriostatic water or sterile water for research use. We recommend our companion BAC Water for consistency. Specific reconstitution volume depends on your research protocol — refer to the Specifications tab for solubility data.
How quickly do orders ship?+
Orders confirmed before 2:00 PM CT ship the same business day from our facility in Tulsa, OK. Standard US transit is 2-5 business days. Tracking provided at shipment.
Is the COA verified independently?+
Yes. Every lot is tested by HPLC for purity (target ≥99%) and mass spectrometry for molecular identity before release. The COA is generated from the actual lot data, not a generic template.
Can I get bulk or institutional pricing?+
Yes — qualified research facilities and high-volume orders receive tiered pricing. Contact us with your institution information and target quantities.
Every lot is independently verified — HPLC purity, mass spec identity, lot number, storage parameters. Click below to view or download.
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