Kisspeptin is a neuropeptide encoded by the KISS1 gene and serves as an endogenous ligand for the GPR54 receptor (also known as the kisspeptin receptor or KISS1R). It is produced in several isoforms — kisspeptin-54, -14, -13, and -10 — of which kisspeptin-10 represents the C-terminal decapeptide with full receptor binding activity. Kisspeptin plays a key role in the regulation of the hypothalamic-pituitary-gonadal (HPG) axis. Heartland Bio Labs supplies Kisspeptin (kisspeptin-10 form) as a lyophilized research compound of verified purity.
Research Use Only — Not for Human Consumption
Kisspeptin (Kisspeptin-10)
- ≥99% HPLC
- Mass Spec Verified
- COA Per Lot
- US Lab
Kisspeptin is a neuropeptide encoded by the KISS1 gene and serves as an endogenous ligand for the GPR54 receptor (also known as the kisspeptin receptor or KISS1R). It is produced in several isoforms — kisspeptin-54, -14, -13, and -10 — of which kisspeptin-10 represents the C-terminal decapeptide with full receptor binding activity. Kisspeptin plays a key role in the regulation of the hypothalamic-pituitary-gonadal (HPG) axis. Heartland Bio Labs supplies Kisspeptin (kisspeptin-10 form) as a lyophilized research compound of verified purity.
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Kisspeptin is one of the most intensively studied neuropeptides in neuroendocrine research. Research has characterized its role as the primary positive regulator of GnRH (gonadotropin-releasing hormone) secretion from hypothalamic neurons, placing it upstream in the HPG axis cascade. Published literature has examined kisspeptin signaling in neuroendocrine axis models, gonadotropin signaling, HPG axis interactions, and metabolic-neuroendocrine axis interactions in rodent and primate models.
This compound is supplied strictly for research purposes. No clinical or therapeutic application is implied or represented.
Product Characteristics
- Peptide class: Neuropeptide (kisspeptin-10 isoform); GPR54/KISS1R agonist
- Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
- Form: Lyophilized powder
- Appearance: White to off-white powder
- Reconstitution medium: Sterile water or 0.1% BSA/PBS (research standard)
| Purity | ≥99% HPLC |
|---|
Handling Information
Handle Kisspeptin under standard laboratory conditions with appropriate PPE. Reconstitute carefully and avoid repeated freeze-thaw cycles. This compound is intended for qualified research use only.
Storage Requirements
- Long-term (lyophilized): Store at -20°C, protected from light and moisture
- Short-term (reconstituted): Store at 4°C; use within 14 days
- Keep in original sealed vial until point of use
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Based on 21 verified researcher reviews
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How should I store this peptide?+
Lyophilized peptides should be stored at −20°C in a dry, light-protected environment. Avoid repeated freeze-thaw cycles. Once reconstituted, store at 2-8°C and use within 4-8 weeks depending on the compound.
What should I reconstitute it with?+
Bacteriostatic water or sterile water for research use. We recommend our companion BAC Water for consistency. Specific reconstitution volume depends on your research protocol — refer to the Specifications tab for solubility data.
How quickly do orders ship?+
Orders confirmed before 2:00 PM CT ship the same business day from our facility in Tulsa, OK. Standard US transit is 2-5 business days. Tracking provided at shipment.
Is the COA verified independently?+
Yes. Every lot is tested by HPLC for purity (target ≥99%) and mass spectrometry for molecular identity before release. The COA is generated from the actual lot data, not a generic template.
Can I get bulk or institutional pricing?+
Yes — qualified research facilities and high-volume orders receive tiered pricing. Contact us with your institution information and target quantities.
View this product's Certificate of Analysis
Every lot is independently verified — HPLC purity, mass spec identity, lot number, storage parameters. Click below to view or download.
Look up COA in portal →Customer Reviews
4.7
★★★★★
Based on 21 verified researcher reviews
Customer reviews coming soon. Be the first to share your research experience.
Research Use Only: This product is sold by Heartland Bio Labs for research and laboratory use only. Not intended for human or veterinary consumption, administration, or therapeutic use. This product has not been evaluated by the Food and Drug Administration. Not a drug. Not a dietary supplement. Researchers are responsible for compliance with all applicable regulations.
