PT-141, also known by the name bremelanotide in the research literature, is a synthetic cyclic heptapeptide agonist of the melanocortin receptor family, with particular activity at the MC3 and MC4 receptors. It was developed from the melanocortin analogue Melanotan II, and it occupies a distinctive place in peptide research: most compounds in this catalog act on metabolic, repair, or neurotrophic pathways, while PT-141 is the catalog's window into central melanocortin signaling. Heartland Bio Labs supplies PT-141 for laboratory research in 10mg vials with independent verification.
What PT-141 is
PT-141 descends directly from Melanotan 2, and the structural change between them is what shifted the research focus. Our Melanotan 2 vs PT-141 comparison covers the lineage and the differences that matter.
The melanocortin system is a signaling network built around alpha-MSH and its receptors, MC1 through MC5, governing a wide range of processes studied across pigmentation, energy balance, inflammation, and central nervous system research. PT-141 is a cyclized, modified analogue in that family: the ring structure gives it stability the linear parent lacks, and its receptor profile concentrates on MC3R and MC4R, the receptors most studied in central signaling research. Structural background is in our PT-141 research overview.
Product characteristics
- Synthetic cyclic heptapeptide, melanocortin receptor agonist (MC3R/MC4R focus)
- Derived from the Melanotan II lineage of alpha-MSH analogues
- Approximate molecular weight: 1,025.2 g/mol
- Supplied as white lyophilized powder in sealed vials
- Available strength: 10mg; a 5mg vial appears on the selector with a notify option when not in stock
- HPLC purity and mass spectrometry identity, tested by an independent laboratory
- For laboratory research use only
The melanocortin family on this site
PT-141 is not the only melanocortin-derived compound we stock. KPV is the C-terminal tripeptide of alpha-MSH itself, studied on the inflammation-signaling side of the family, and Kisspeptin-10 sits in the adjacent neuroendocrine research space. Laboratories mapping receptor-family signaling often work across these compounds, and each is tested and documented the same way.
How this product is verified
A cyclic peptide is a slightly harder analytical target than a linear one, which makes independent testing more valuable, not less. PT-141 is verified by HPLC for purity and mass spectrometry for identity at an independent laboratory, with certificates published in our COA portal before purchase. Our guide on reading a peptide certificate of analysis explains the document line by line, and the broader checklist lives in how to vet a research peptide supplier.
Pricing, storage, and shipping
The 10mg vial is $85, in stock, shipping same-day from the Tulsa, Oklahoma area on orders placed before 2:00 PM Central. Store lyophilized vials sealed, cool, dry, and away from light, refrigerated for the long term; reconstitute with bacteriostatic water and refrigerate the solution, using it within the window your protocol defines. Institutional quantities run through our wholesale program.
Reconstitution math
Work out concentration (mg/mL), amount per volume and molarity for any vial size with the general peptide calculator. For the bench procedure see how to reconstitute peptides.
Research use only
PT-141 from Heartland Bio Labs is sold strictly for laboratory research and identification purposes. It is not a drug, it has not been evaluated by the FDA, and it is not for human or veterinary use of any kind. By purchasing, you affirm that you are qualified to handle research compounds and agree to our research use policy.
