PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide and melanocortin receptor agonist. It is structurally derived from Melanotan II (MT-2) but differs in that the C-terminal amide is replaced with a hydroxyl group, making it non-cyclic at the C-terminus while retaining the core cyclic disulfide structure. PT-141 acts as an agonist at melanocortin receptor subtypes (particularly MC1R, MC3R, MC4R, and MC5R). Heartland Bio Labs supplies PT-141 as a lyophilized research compound of verified purity.
Research Use Only — Not for Human Consumption
PT-141 (Bremelanotide)
- ≥99% HPLC
- Mass Spec Verified
- COA Per Lot
- US Lab
PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide and melanocortin receptor agonist. It is structurally derived from Melanotan II (MT-2) but differs in that the C-terminal amide is replaced with a hydroxyl group, making it non-cyclic at the C-terminus while retaining the core cyclic disulfide structure. PT-141 acts as an agonist at melanocortin receptor subtypes (particularly MC1R, MC3R, MC4R, and MC5R). Heartland Bio Labs supplies PT-141 as a lyophilized research compound of verified purity.
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PT-141 has been studied extensively in the context of melanocortin receptor pharmacology, central nervous system melanocortin signaling, and endocrine axis research. It is the subject of a substantial published literature covering MC4R and MC3R agonism, hypothalamic signaling, and behavioral models in rodents and primates. PT-141 has an extensive published reference literature spanning multiple preclinical and translational research models.
This compound is supplied strictly for research purposes. No clinical or therapeutic application is implied or represented.
Product Characteristics
- Peptide class: Synthetic cyclic heptapeptide; melanocortin receptor agonist
- Receptor targets: MC1R, MC3R, MC4R, MC5R
- Form: Lyophilized powder
- Appearance: White to off-white powder
- Reconstitution medium: Sterile water or saline (research standard)
| Purity | ≥99% HPLC |
|---|
Handling Information
Handle PT-141 under standard laboratory conditions with appropriate PPE. Avoid repeated freeze-thaw cycles once reconstituted. This compound is intended for use by qualified research professionals only.
Storage Requirements
- Long-term (lyophilized): Store at -20°C, protected from light and moisture
- Short-term (reconstituted): Store at 4°C; use within 14 days
- Keep in original sealed vial until point of use
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How should I store this peptide?+
Lyophilized peptides should be stored at −20°C in a dry, light-protected environment. Avoid repeated freeze-thaw cycles. Once reconstituted, store at 2-8°C and use within 4-8 weeks depending on the compound.
What should I reconstitute it with?+
Bacteriostatic water or sterile water for research use. We recommend our companion BAC Water for consistency. Specific reconstitution volume depends on your research protocol — refer to the Specifications tab for solubility data.
How quickly do orders ship?+
Orders confirmed before 2:00 PM CT ship the same business day from our facility in Tulsa, OK. Standard US transit is 2-5 business days. Tracking provided at shipment.
Is the COA verified independently?+
Yes. Every lot is tested by HPLC for purity (target ≥99%) and mass spectrometry for molecular identity before release. The COA is generated from the actual lot data, not a generic template.
Can I get bulk or institutional pricing?+
Yes — qualified research facilities and high-volume orders receive tiered pricing. Contact us with your institution information and target quantities.
View this product's Certificate of Analysis
Every lot is independently verified — HPLC purity, mass spec identity, lot number, storage parameters. Click below to view or download.
Look up COA in portal →Customer Reviews
4.7
★★★★★
Based on 31 verified researcher reviews
Customer reviews coming soon. Be the first to share your research experience.
Research Use Only: This product is sold by Heartland Bio Labs for research and laboratory use only. Not intended for human or veterinary consumption, administration, or therapeutic use. This product has not been evaluated by the Food and Drug Administration. Not a drug. Not a dietary supplement. Researchers are responsible for compliance with all applicable regulations.
