Retatrutide is a synthetic 39-amino acid triple receptor agonist targeting the GIP (Glucose-Dependent Insulinotropic Polypeptide) receptor, GLP-1 (Glucagon-Like Peptide-1) receptor, and glucagon receptor simultaneously. It incorporates a fatty acid chain modification for extended plasma half-life via albumin binding. Retatrutide represents a novel class of triple incretin agonist research compounds, and is among the most recently characterized peptides in this research category. Heartland Bio Labs supplies Retatrutide as a lyophilized research compound of verified purity.
Research Use Only — Not for Human Consumption
Retatrutide
- ≥99% HPLC
- Mass Spec Verified
- COA Per Lot
- US Lab
Retatrutide is a synthetic 39-amino acid triple receptor agonist targeting the GIP (Glucose-Dependent Insulinotropic Polypeptide) receptor, GLP-1 (Glucagon-Like Peptide-1) receptor, and glucagon receptor simultaneously. It incorporates a fatty acid chain modification for extended plasma half-life via albumin binding. Retatrutide represents a novel class of triple incretin agonist research compounds, and is among the most recently characterized peptides in this research category. Heartland Bio Labs supplies Retatrutide as a lyophilized research compound of verified purity.
$148.00
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Retatrutide is studied in preclinical and clinical research settings examining the simultaneous pharmacology of three metabolic receptor pathways. Published research has investigated its effects on insulin secretion, glucagon regulation, metabolic signaling, and receptor co-agonism mechanisms in animal and human study models. The addition of glucagon receptor agonism to the dual-incretin model (GIP + GLP-1) represents a distinct and actively studied pharmacological approach in metabolic biology research.
This compound is supplied strictly for research purposes. No clinical or therapeutic application is implied or represented.
Product Characteristics
- Peptide class: Synthetic triple GIP/GLP-1/glucagon receptor agonist (39 amino acids)
- Modification: C20 fatty diacid moiety via linker for albumin binding and extended half-life
- Form: Lyophilized powder
- Appearance: White to off-white powder
- Reconstitution medium: Bacteriostatic water or sterile water (research standard)
| Purity | ≥99% HPLC |
|---|
Handling Information
Handle Retatrutide under standard laboratory conditions with appropriate PPE. Aseptic reconstitution technique recommended. Avoid repeated freeze-thaw cycles. This compound is intended for qualified research use only.
Storage Requirements
- Long-term (lyophilized): Store at -20°C, protected from light and moisture
- Short-term (reconstituted): Store at 4°C; use within 28 days
- Keep in original sealed vial until point of use
4.9
★★★★★
Based on 118 verified researcher reviews
Dr. H. Bauer
✓ Verified buyer
2026-04-27
★★★★★
Heartland has this correctly. Mass spec confirms full molecular identity.
Drew C.
✓ Verified buyer
2026-04-14
★★★★★
Price is fair for US-made with COA per lot. No hidden fees. COA posted before purchase made the decision easy.
Dr. F. Adeyemo
✓ Verified buyer
2026-03-31
★★★★★
Vial arrived sealed, labels clear and lot numbers match the COA exactly. Professional packaging.
How should I store this peptide?+
Lyophilized peptides should be stored at −20°C in a dry, light-protected environment. Avoid repeated freeze-thaw cycles. Once reconstituted, store at 2-8°C and use within 4-8 weeks depending on the compound.
What should I reconstitute it with?+
Bacteriostatic water or sterile water for research use. We recommend our companion BAC Water for consistency. Specific reconstitution volume depends on your research protocol — refer to the Specifications tab for solubility data.
How quickly do orders ship?+
Orders confirmed before 2:00 PM CT ship the same business day from our facility in Tulsa, OK. Standard US transit is 2-5 business days. Tracking provided at shipment.
Is the COA verified independently?+
Yes. Every lot is tested by HPLC for purity (target ≥99%) and mass spectrometry for molecular identity before release. The COA is generated from the actual lot data, not a generic template.
Can I get bulk or institutional pricing?+
Yes — qualified research facilities and high-volume orders receive tiered pricing. Contact us with your institution information and target quantities.
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View this product's Certificate of Analysis
Every lot is independently verified — HPLC purity, mass spec identity, lot number, storage parameters. Click below to view or download.
Look up COA in portal →Customer Reviews
4.9
★★★★★
Based on 118 verified researcher reviews
Dr. H. Bauer
✓ Verified buyer
2026-04-27
★★★★★
Heartland has this correctly. Mass spec confirms full molecular identity.
Drew C.
✓ Verified buyer
2026-04-14
★★★★★
Price is fair for US-made with COA per lot. No hidden fees. COA posted before purchase made the decision easy.
Dr. F. Adeyemo
✓ Verified buyer
2026-03-31
★★★★★
Vial arrived sealed, labels clear and lot numbers match the COA exactly. Professional packaging.
Research Use Only: This product is sold by Heartland Bio Labs for research and laboratory use only. Not intended for human or veterinary consumption, administration, or therapeutic use. This product has not been evaluated by the Food and Drug Administration. Not a drug. Not a dietary supplement. Researchers are responsible for compliance with all applicable regulations.
