Ipamorelin is among the most studied compounds in secretagogue-pathway research, and its appeal is specificity: a small, well-characterized molecule with a cleaner receptor profile than the earlier GHRP series it descends from.
What ipamorelin is
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂, ~711.9 Da) that acts on the ghrelin/growth-hormone-secretagogue receptor (GHS-R) in laboratory models. It emerged from the GHRP research lineage — the same family as GHRP-2 and GHRP-6 — but is prized in research for engaging its target pathway with less of the off-target receptor activity reported for its predecessors. That selectivity is exactly why it appears so often in mechanism-focused research designs.
Secretagogue vs. GHRH analog — a research design distinction
Ipamorelin (ghrelin-receptor route) is frequently studied alongside GHRH-pathway analogs like CJC-1295 and tesamorelin — two different receptor systems converging on related downstream biology, which is why paired-compound study designs (and combined research blends) are common in the literature and in research catalogs.
Stability and handling
- Lyophilized: a robust small peptide — refrigerated or frozen storage away from light and moisture.
- Reconstituted: dissolves readily in bacteriostatic water for laboratory use; refrigerate and avoid repeated freeze-thaw.
- Note the unusual residues: Aib and D-amino acids are part of the design (they resist enzymatic degradation) — and they also make mass-spec identity confirmation especially clean.
Lot quality checklist
- Identity: observed mass ~711.9 Da on the certificate.
- Purity: ≥99% HPLC — easily achievable on a pentapeptide; expect it.
- Traceability: lot number on the vial retrieves a live certificate in the COA portal. (New to reading these? Start with the COA guide.)
Research availability
Ipamorelin research material (5mg) — ≥99% HPLC purity and mass-spec identity on every lot, shipped same-day from Tulsa, Oklahoma.
Ipamorelin is supplied strictly for in vitro laboratory research — not for human or veterinary use.