CJC-1295 and Ipamorelin appear together so often in research-supply catalogs that the pairing is practically its own product — and in our case it is: a dual blend supplied in one lyophilized vial. The two are distinct molecules with different structures and different receptor targets, which is precisely why the combination attracts research interest. This overview covers what each component is, why the pairing recurs in the literature, and what to look for on a certificate.
The two components
CJC-1295 (No DAC), also catalogued as Mod GRF 1-29, is a synthetic 29-amino-acid analogue of the biologically active fragment of growth-hormone-releasing hormone (GHRH), modified at four positions for stability. The “No DAC” designation distinguishes it from the DAC-conjugated form, which carries a drug-affinity-complex modification that substantially extends its half-life in circulation models. We stock both forms separately; the blend uses the No DAC form.
Ipamorelin is a synthetic pentapeptide (five amino acids) belonging to the growth-hormone-secretagogue class studied for its selectivity at the ghrelin receptor (GHS-R). Its research profile is built on that selectivity: in receptor studies it shows activity at GHS-R with comparatively little activity at related targets.
Why the pairing recurs in research
The two compounds act at different receptors — one a GHRH-receptor analogue, one a ghrelin-receptor agonist — and study designs examining that axis frequently use agents from both classes to characterize the pathways separately and together. A pre-blended vial fixes the ratio between the two components across an experiment, which is the practical reason blends exist in research supply at all.
Analytical profile and verifying a lot
A blend certificate has to treat the components individually. Identity for each molecule is established by mass spectrometry — a 29-residue analogue and a pentapeptide are trivially distinguishable by mass — and the composition is profiled chromatographically. A certificate that reports one unlabeled purity number for a two-component vial has not described the vial.
The checks are the standard ones: the lot number on the certificate matches the vial in hand, the issuing laboratory is named with its original report attached, and the report verifies with the laboratory directly. Every lot of the blend we sell publishes its certificate in the certificate archive.
Handling notes
Supplied lyophilized; store cool, dark and dry until laboratory use. Standard research practice reconstitutes with bacteriostatic water. All handling is for qualified laboratory settings.
Frequently asked research questions
Is CJC-1295 + Ipamorelin one compound? No — two distinct peptides in one vial, with separate structures, literatures, and analytical signatures.
Which CJC-1295 form is in the blend? The No DAC form (Mod GRF 1-29). The DAC-conjugated form is a different molecule with a different stability profile and is catalogued separately.
How should a certificate treat a dual blend? Component-by-component: identity for each by mass spec, composition by chromatography, tied to the lot number on the vial. Ask any supplier how their blend certificates handle this before buying.
Where can I read about the single compounds? See the CJC-1295 overview and the Ipamorelin overview.
All products discussed are for laboratory research use only and are not for human or veterinary consumption. Nothing here describes or endorses any use in humans or animals.