Tesamorelin is a synthetic analogue of growth-hormone-releasing hormone (GHRH) that keeps the hormone's complete 44-amino acid sequence and adds one modification: a trans-3-hexenoyl group on the N-terminus. That single change is the whole point of the molecule, protecting it from the enzyme that destroys native GHRH within minutes. Among the growth-hormone-axis peptides in this catalog, tesamorelin is the most complete GHRH analogue and the one with the deepest formal research record. Heartland Bio Labs supplies it for laboratory research in 10mg vials with a published certificate of analysis.
What tesamorelin is
Native GHRH is cleared almost immediately in circulation, cleaved by the enzyme DPP-4 at its N-terminal end. Tesamorelin's hexenoyl modification shields exactly that cleavage site while leaving the rest of the 44-residue sequence intact, which is why it behaves like GHRH at the receptor but persists long enough to study. Where truncated analogues keep only the fragment of the hormone needed for receptor binding, tesamorelin keeps everything. Structural detail is in our tesamorelin research overview.
The GH-axis family, mapped
Tesamorelin is one of several GHRH analogues in the catalog, each with a different stabilization strategy. Our GH-axis peptide family map shows how they relate and what separates the two branches of the family.
The growth-hormone-axis research peptides split into two mechanistic camps, and knowing which camp a compound sits in is the first step of any study design. The GHRH-analogue side works through the GHRH receptor: tesamorelin (the full-length stabilized analogue), sermorelin (the shortest functional fragment), and CJC-1295 (a fragment engineered for very long half-life). The secretagogue side works through the ghrelin receptor instead: ipamorelin is the selective example we stock, and the two pathways are frequently studied in combination via our CJC-1295 + ipamorelin blend.
Product characteristics
- Synthetic 44-amino acid GHRH analogue with N-terminal trans-3-hexenoyl modification
- Full native GHRH sequence retained; DPP-4 cleavage site protected
- Supplied as white lyophilized powder in sealed vials
- Available strength: 10mg; a 5mg vial appears on the selector with a notify option when not in stock
- HPLC purity and mass spectrometry identity, tested by an independent laboratory, certificate published
- For laboratory research use only
How this product is verified
Tesamorelin is one of the compounds with a certificate already published in our COA portal, issued by an independent analytical laboratory with HPLC purity and mass spectrometry identity confirmation. A 44-residue peptide is a demanding synthesis, which makes independent verification worth more here than on the small peptides: more residues means more places a synthesis can go subtly wrong in ways only real analysis catches. Our guide on reading a peptide certificate of analysis shows you exactly what to look for.
Pricing, storage, and shipping
The 10mg vial is $155, in stock, shipping same-day from the Tulsa, Oklahoma area on orders before 2:00 PM Central. Store lyophilized vials sealed, cool, dry, and away from light, refrigerated long term; reconstitute with bacteriostatic water, swirl gently, refrigerate the solution, and use it within your protocol's window. Larger programs run through our wholesale program, and our supplier vetting guide is the standard to hold us and everyone else to.
Reconstitution math
Work out concentration (mg/mL), amount per volume and molarity for any vial size with the general peptide calculator. For the bench procedure see how to reconstitute peptides.
Research use only
Tesamorelin from Heartland Bio Labs is sold strictly for laboratory research and identification purposes. It is not a drug, it has not been evaluated by the FDA, and it is not for human or veterinary use of any kind. By purchasing, you affirm that you are qualified to handle research compounds and agree to our research use policy.
