MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino acid peptide encoded within the mitochondrial genome, specifically derived from the 12S rRNA gene. It represents a class of mitochondria-derived peptides (MDPs) and has attracted significant research interest for its role in mitochondrial-nuclear communication and cellular metabolic regulation. Heartland Bio Labs supplies MOTS-c as a lyophilized research compound of verified purity.
Research Use Only — Not for Human Consumption
MOTS-c
- ≥99% HPLC
- Mass Spec Verified
- COA Per Lot
- US Lab
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino acid peptide encoded within the mitochondrial genome, specifically derived from the 12S rRNA gene. It represents a class of mitochondria-derived peptides (MDPs) and has attracted significant research interest for its role in mitochondrial-nuclear communication and cellular metabolic regulation. Heartland Bio Labs supplies MOTS-c as a lyophilized research compound of verified purity.
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MOTS-c is one of the most actively studied mitochondria-derived peptides in contemporary mitochondrial and metabolic biology research. Published research has investigated its roles in AMPK pathway activation, AMPK pathway signaling, mitochondrial function, and cellular stress response in in vitro and in vivo models. Studies have examined MOTS-c levels in aged cell models and its interaction with metabolic signaling pathways in muscle cell models.
This compound is supplied strictly for research purposes. No clinical or therapeutic application is implied or represented.
Product Characteristics
- Peptide class: Mitochondria-derived peptide (MDP); 16 amino acids
- Genomic origin: Encoded in mitochondrial 12S rRNA gene open reading frame
- Form: Lyophilized powder
- Appearance: White to off-white powder
- Reconstitution medium: Sterile water or PBS (research standard)
| Purity | ≥99% HPLC |
|---|
Handling Information
Handle MOTS-c under standard laboratory conditions with appropriate PPE. Reconstitute with sterile water or PBS. Avoid repeated freeze-thaw cycles. This compound is intended for qualified research use only.
Storage Requirements
- Long-term (lyophilized): Store at -20°C, protected from light and moisture
- Short-term (reconstituted): Store at 4°C; use within 14 days
- Keep in original sealed vial until point of use
4.8
★★★★★
Based on 34 verified researcher reviews
Customer reviews coming soon. Be the first to share your research experience.
How should I store this peptide?+
Lyophilized peptides should be stored at −20°C in a dry, light-protected environment. Avoid repeated freeze-thaw cycles. Once reconstituted, store at 2-8°C and use within 4-8 weeks depending on the compound.
What should I reconstitute it with?+
Bacteriostatic water or sterile water for research use. We recommend our companion BAC Water for consistency. Specific reconstitution volume depends on your research protocol — refer to the Specifications tab for solubility data.
How quickly do orders ship?+
Orders confirmed before 2:00 PM CT ship the same business day from our facility in Tulsa, OK. Standard US transit is 2-5 business days. Tracking provided at shipment.
Is the COA verified independently?+
Yes. Every lot is tested by HPLC for purity (target ≥99%) and mass spectrometry for molecular identity before release. The COA is generated from the actual lot data, not a generic template.
Can I get bulk or institutional pricing?+
Yes — qualified research facilities and high-volume orders receive tiered pricing. Contact us with your institution information and target quantities.
View this product's Certificate of Analysis
Every lot is independently verified — HPLC purity, mass spec identity, lot number, storage parameters. Click below to view or download.
Look up COA in portal →Customer Reviews
4.8
★★★★★
Based on 34 verified researcher reviews
Customer reviews coming soon. Be the first to share your research experience.
Research Use Only: This product is sold by Heartland Bio Labs for research and laboratory use only. Not intended for human or veterinary consumption, administration, or therapeutic use. This product has not been evaluated by the Food and Drug Administration. Not a drug. Not a dietary supplement. Researchers are responsible for compliance with all applicable regulations.
